T2DM

Type 2 diabetes mellitus (T2DM) is a metabolic disease principally provoked by impaired insulin signaling and insulin production discontinuation in severe cases. T2DM is associated with severe complications, including dyslipidemia and stroke. We need to focus on the concomitant rise of obesity and type 2 diabetes—obese diabetes. Obesity is an independent risk factor for developing T2DM; in fact, >90% of T2DM are overweight or obese. It is profoundly established that the pathological mechanism of obesity, particularly insulin resistance, expedites the development of T2DM.