Obesity & NAFLD

Obesity is a primary healthcare issue worldwide, and its prevalence is continuously increasing at an alarming rate. Enlarged adipocytes exacerbate glucose and lipid homeostasis, inducing dyslipidemia, type II diabetes, and cardiovascular diseases. The mechanism of obesity is intimately associated with nutrient-sensing pathways, which regulate energy metabolism, cell growth, and proliferation through stimulating the mammalian target of rapamycin (mTOR), growth factors, and insulin pathways.